Target SpeciesHuman
SpecificityCD207
Other NamesCD207, Langerin
FluorochromePE
Regulatory StatusASR
Size2 mL
FormatLiquid
Flow Product LineIOTest
CloneDCGM4
IsotypeIgG1 Mouse
Clone DescriptionThe DCGM4 antibody stains exclusively immature DCs of the LC lineage. Both intracytoplasmic and surface membrane staining is observed. DCGM4 acts as a ligand for Langerin, triggering rapid endocytosis within 20 minutes at 37oC. The antibody has been used in intracellular immunofluorescence analyzed in confocal microscopy. The DCGM4 antibody has been used to determine the differentiation of the CD1a+/CD11c+ subset of blood DCs into LCs, and in the characterization of DCs infiltrating breast carcinoma tissue.
Volume2 mL